ST. LOUIS (AP) -- Peyton Manning threw for three touchdowns but didn't get a chance for a sixth straight 300-yard passing game in the Indianapolis Colts' 42-6 rout of the winless St. Louis Rams on Sunday.

It wouldn't have been appropriate for Manning to try to tie the NFL record the way his unbeaten team was beating up on the woeful Rams. He was 23 for 34 for 235 yards.

The Colts defense got its first score of the year on rookie Jacob Lacey's 35-yard interception return. Looking fresh coming off their bye, the Colts (6-0) won their 15th straight regular-season game and set a franchise record with their eighth straight road victory.

There were plenty of cheers from a sellout crowd that included a healthy contingent of Indianapolis fans, many who lingered to salute players after the game.

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